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Search Results for " eye disease "

11

Compounds

Cat No. Product Name Synonyms Targets
T5194 SPHINX31 Serine/threonin kinase
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).
T3977 Lifitegrast SHP-606,SAR 1118 Integrin
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist.
TMS2180 Zeaxanthin Anchovyxanthin,All-Trans-Zeaxanthin Antioxidant , Endogenous Metabolite
1. Lutein and Zeaxanthin (All-Trans-Zeaxanthin) in neural tissue may have biological effects that include antioxidation, anti-inflammation, and structural actions. 2. Lutein and Zeaxanthin may be protective against eye d...
T7423 Diquafosol tetrasodium INS365 P2Y Receptor
Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film stability and visual function, as a topical treatment of dr...
T68037L CBS-1114 HCl N-Phenylbenzamidrazone hydrochloride,cbs-1114 HCl(46721-85-1 Free base) Lipoxygenase
CBS-1114 HCl (N-Phenylbenzamidrazone hydrochloride) is a 5-lipoxygenase inhibitor and an anti-inflammatory compound in a good eye-permeable model.CBS-1114 HCl maintains and improves cardiac function, attenuates cardiac d...
T28496 R-932348 choline R-932348,R 348,R 932348,R932348,R-348,R348
R-932348 choline, a dual JAK/SYK inhibitor, is used potentially for treatment of dry eye disease.
T39293 Tivanisiran SYL1001,Tivanisiran
Tivanisiran (SYL1001) is a siRNA developed specifically to inhibit the expression of transient receptor potential vanilloid 1 (TRPV1) to explore its implications in dry eye disease research.
T60864 Sequifenadine
Sequifenadine has the potential in researching of inflammatory eye disease with allergic symptoms that is a H1-antihistamine [1] [2].
T74867 UBX1325
UBX1325, a Bcl-xL inhibitor, enhances apoptosis in senescent cells, serving as an effective anti-aging agent. It holds potential for age-related eye disease research, including diabetic macular oedema (DME), age-related ...
T70346 TOP1362
TOP1362 is a Narrow Spectrum Kinase Inhibitors Demonstrate Promise for the Treatment of Dry Eye Disease and Other Ocular Inflammatory Disorders. TOP1362 strongly inhibited the kinase targets p38α, Syk, Src, and Lck, bloc...
T79235 JAK-IN-30 JAK
JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50) values of 2 nM for JAK2, 15 nM for JAK1, 18 nM for JAK3, an...
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