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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5194 | SPHINX31 | Serine/threonin kinase | |
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM). | |||
T3977 | Lifitegrast | SHP-606,SAR 1118 | Integrin |
Lifitegrast (SAR 1118) is a lymphocyte, function-associated antigen-1 antagonist. | |||
TMS2180 | Zeaxanthin | Anchovyxanthin,All-Trans-Zeaxanthin | Antioxidant , Endogenous Metabolite |
1. Lutein and Zeaxanthin (All-Trans-Zeaxanthin) in neural tissue may have biological effects that include antioxidation, anti-inflammation, and structural actions. 2. Lutein and Zeaxanthin may be protective against eye d... | |||
T7423 | Diquafosol tetrasodium | INS365 | P2Y Receptor |
Diquafosol Tetrasodium is a P2Y2 receptor agonist that stimulates the secretion of mucins from ocular tissues Diquafosol tetrasodium (INS365) improves tear film stability and visual function, as a topical treatment of dr... | |||
T68037L | CBS-1114 HCl | N-Phenylbenzamidrazone hydrochloride,cbs-1114 HCl(46721-85-1 Free base) | Lipoxygenase |
CBS-1114 HCl (N-Phenylbenzamidrazone hydrochloride) is a 5-lipoxygenase inhibitor and an anti-inflammatory compound in a good eye-permeable model.CBS-1114 HCl maintains and improves cardiac function, attenuates cardiac d... | |||
T28496 | R-932348 choline | R-932348,R 348,R 932348,R932348,R-348,R348 | |
R-932348 choline, a dual JAK/SYK inhibitor, is used potentially for treatment of dry eye disease. | |||
T39293 | Tivanisiran | SYL1001,Tivanisiran | |
Tivanisiran (SYL1001) is a siRNA developed specifically to inhibit the expression of transient receptor potential vanilloid 1 (TRPV1) to explore its implications in dry eye disease research. | |||
T60864 | Sequifenadine | ||
Sequifenadine has the potential in researching of inflammatory eye disease with allergic symptoms that is a H1-antihistamine [1] [2]. | |||
T74867 | UBX1325 | ||
UBX1325, a Bcl-xL inhibitor, enhances apoptosis in senescent cells, serving as an effective anti-aging agent. It holds potential for age-related eye disease research, including diabetic macular oedema (DME), age-related ... | |||
T70346 | TOP1362 | ||
TOP1362 is a Narrow Spectrum Kinase Inhibitors Demonstrate Promise for the Treatment of Dry Eye Disease and Other Ocular Inflammatory Disorders. TOP1362 strongly inhibited the kinase targets p38α, Syk, Src, and Lck, bloc... | |||
T79235 | JAK-IN-30 | JAK | |
JAK-IN-30 (compound 31) is a water-soluble inhibitor of Janus kinases (JAKs), demonstrating inhibitory potency with half-maximal inhibitory concentration (IC50) values of 2 nM for JAK2, 15 nM for JAK1, 18 nM for JAK3, an... |